Tobacco exposure and sleep disturbance in 498 208 UK Biobank participants

Sleep Disturbance in Travelers

Correction: Cognitive Test Scores in UK Biobank: Data Reduction in 480,416 Participants and Longitudinal Stability in 20,346 Participants

[This corrects the article DOI: 10.1371/journal.pone.0154222.].

Associations between single and multiple cardiometabolic diseases and cognitive abilities in 474 129 UK Biobank participants

Aims Cardiometabolic diseases (hypertension, coronary artery disease [CAD] and diabetes are known to associate with poorer cognitive ability but there are limited data on whether having more than one of these conditions is associated with additive effects. We aimed to quantify the magnitude of their associations with non-demented cognitive abilities and determine the extent to which these assoc...

Ageing and brain white matter structure in 3,513 UK Biobank participants

Quantifying the microstructural properties of the human brain's connections is necessary for understanding normal ageing and disease. Here we examine brain white matter magnetic resonance imaging (MRI) data in 3,513 generally healthy people aged 44.64-77.12 years from the UK Biobank. Using conventional water diffusion measures and newer, rarely studied indices from neurite orientation dispersio...

Central adiposity and the overweight risk paradox in aging: follow-up of 130,473 UK Biobank participants

Background: For older groups, being overweight [body mass index (BMI; in kg/m2): 25 to <30] is reportedly associated with a lower or similar risk of mortality than being normal weight (BMI: 18.5 to <25). However, this "risk paradox" is partly explained by smoking and disease-associated weight loss. This paradox may also arise from BMI failing to measure fat redistribution to a centralized posit...